Normal pressure hydrocephalus (NPH) is a buildup of fluid in the brain that develops slowly in older adults and is easy to mistake for aging or dementia. It classically causes three things: a change in walking, mild memory and thinking problems, and loss of bladder control. It matters because, unlike most causes of these symptoms, NPH can sometimes be improved with treatment.
A treatable cause of walking, memory, and bladder problems that is often mistaken for ordinary aging.
Deep inside the brain are fluid-filled spaces called ventricles that hold cerebrospinal fluid (CSF). In normal pressure hydrocephalus, this fluid gradually builds up and the ventricles enlarge — but, unlike other forms of hydrocephalus, the pressure inside the head stays close to normal. That is what makes NPH different, and harder to recognize.
Because it comes on slowly in older adults, NPH is frequently mistaken for normal aging, Alzheimer's disease, or Parkinson's disease. The distinction is important: the symptoms of NPH can improve when the extra fluid is drained, which is not true of most other causes of the same symptoms. Recognizing NPH — and testing for it — is the key step.
At Brown Neurosurgery, evaluation focuses on two questions: do the symptoms and imaging fit NPH, and — just as important — is a person likely to benefit from draining fluid? A short, low-risk test (described below) helps answer the second question before any decision about surgery is made.
NPH tends to cause three symptoms, sometimes remembered as "wet, wobbly, and wacky." Select one to see what it looks like and how likely it is to respond to treatment.
Select a symptom at left to learn more about it.
Diagnosis has two parts: confirming the picture fits NPH, and testing whether draining fluid actually helps you.
A scan shows whether the ventricles are enlarged out of proportion to the normal shrinkage of the brain that happens with age. It also helps rule out other causes such as a stroke, tumor, or a different kind of hydrocephalus.
Your team may film or time your walking and turning before and after fluid is removed, because a measurable improvement in gait is one of the most useful signs that a shunt will help.
In a large-volume spinal tap (also called a tap test), a modest amount of CSF is removed through a needle in the lower back — the same idea as a routine lumbar puncture. If your walking or thinking improves over the next hours to days, that suggests a shunt is likely to help.
When a single tap is not clear-cut, a few days of continuous CSF drainage through a small temporary lumbar catheter, in the hospital, gives a longer look at whether symptoms respond. Tell your team if you take blood thinners before any of these tests.
Several factors make a good response to treatment more or less likely. Select one to learn how it weighs in. This is a guide to the conversation, not a substitute for evaluation.
Select a factor at left to see how it affects candidacy.
NPH is treated by placing a shunt — a soft tube with a valve, entirely under the skin — that drains the extra CSF from a ventricle to the abdomen, where it is absorbed. Select each step to see what happens and why.
In well-selected patients a shunt can restore meaningful function — but the benefit varies from person to person, and it is important to have realistic expectations.
Gait is the symptom that responds best and most reliably, especially in people whose walking improved after the tap or drainage trial. Many notice steadier, less "stuck" walking.
Memory, attention, and bladder control can improve too, but less predictably than gait. A shunt is more likely to stabilize or partly improve thinking than to fully reverse it, particularly if symptoms have been present a long time.
Some people keep their improvement for years; in others the benefit lessens, or another condition of aging adds new symptoms. Ongoing follow-up and valve adjustments help maintain the best result.
As with any shunt: overdrainage (and subdural collections), infection, blockage, and the need for revision. Risks are taken seriously in older adults, which is one reason programmable valves and careful follow-up are used.
CSF disorders such as NPH are evaluated and treated through Brown Neurosurgery, with careful shunt selection and long-term follow-up.
See the full neurosurgery team and request an evaluation on the Brown Neurosurgery website.